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UNMC announces HIV breakthrough

OMAHA, Neb. (WOWT) – On Tuesday, UNMC announced that researchers working together at Temple University have made an important step in developing a cure for HIV.

Dr. Howard Gendelmans group at UNMC. (Photo courtesy of UNMC)

The researchers say that for the first time, they have eliminated "replication competent HIV-1

DNA, the virus responsible for AIDS, from the genome of living animals."

Researchers at the University of Nebraska Medical Center joined the Lewis Katz School of Medicine at Temple University for the study, reported online today in the journal Nature Communications.

"(the study) marks a critical step towards the development of a possible cure for human HIV infection," according to a UNMC press release.

"Our study shows that treatment to suppress HIV replication and gene editing when given sequentially can remove HIV from cells and organs of infected animals," says Dr. Camel Khalili from Comprehensive NeuroAIDS Center at LKSOM, who is also a senior researcher on the study.

Dr. Howard Gendelman from UNMC, also a senior researcher on the project, credited the teamwork.

"This performance could not have been possible without an extraordinary team effort involving virologists, immunologists, molecular biologists, pharmacologists, and pharmaceutical experts," he said. "Only by gathering our resources together could we make this groundbreaking discovery."

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