Home https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Science https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Israeli researchers say they have found a way to reverse the human aging process

Israeli researchers say they have found a way to reverse the human aging process

Israeli researchers say they have managed to reverse the biological aging process successfully – using only oxygen.
New research, led by Prof. Shai Efrati of Tel Aviv University, along with a team from Shamir Medical Center, found that when healthy adults over the age of 64 were placed in a pressure chamber and given clean oxygen for 90 minutes a day, five days a week for three months, the aging process was not only delayed – it was actually reversed.

Specifically, the study focused on whether the process could reverse two key indicators of biological aging: shortening of DNA telomeres and accumulation of resulting senescent cells.

A telomere is the end of a chromosome. Telomeres are made of repeated sequences of non-coding DNA that serve as bumpers to protect the chromosome from damage during replication. Every time replication happens, these bumpers get a hit, making them shorter and shorter.

When the telomere reaches a certain length, the cell can no longer replicate, leading to aging cells: aging, cells that do not function, which ultimately leads to cognitive or other age-related disabilities, and even diseases such as cancer.

About 35 adults over the age of 64 were involved in the study and were administered hyperbaric oxygen therapy (HBOT) using 1

00% oxygen at an environmental pressure higher than an absolute atmosphere, to increase the amount of oxygen dissolved in the body’s tissues.

Every 20 minutes, participants were asked to remove their masks for five minutes and bring their oxygen back to normal levels. During this period, however, the researchers saw that fluctuations in the free oxygen concentration were interpreted at the cellular level as a lack of oxygen – rather than interpreting the absolute oxygen level.

In other words, repeated intermittent hyperoxic (increased oxygen levels) exposures induced many of the mediators and cellular mechanisms normally induced during hypoxia (decreased oxygen levels) – something that Efrati explained is called the hyperoxic-hypoxic paradox.

“The oxygen fluctuation we generated is what matters,” he said Jerusalem Post. “During this process, a state of oxygen deficiency resulted, which caused cell regeneration.”

The practical implications include improvements in attention, information processing speed, and executive functions, which usually decline with aging, and which more than 50% of people over the age of 60 express concern about.

Participants did not undergo changes in lifestyle, diet, or medication during the study, which could have altered the results.

“We are not [just] slows down the decline – we are going backwards in time, “said Efrati.

According to their work, the changes corresponded to how the participants’ bodies were at the mobile level 25 years earlier.

Efrati has been studying how to reverse the aging process for a decade. This study, he said, is the first evidence that the cellular basis of the aging process can be reversed, adding that it “offers hope and opens the door for many young researchers to target aging as a reversible disease.”

It could also enable doctors and researchers to find a way to monitor telomere length and develop medications that can help them grow back when needed.

Will it make people live longer?

The duration of the effect has not yet been determined by long-term follow-ups, Efrati said. But he added: “Probably yes. We know that people with shorter telomeres die earlier, so that makes sense. ”

Another disadvantage of the study was its limited sample size.

Efrati added that the experiment was conducted using a scientifically monitored HBOT chamber and that people should not try this at home. He said: “There is a lot of junk out there” and claims that tubes or bags that are inflated with air are hyperbaric treatments. “This is not what is used in the studies, it is not effective – and moreover, it can be dangerous,” he concluded.

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