Folk medicines and herbal products have been used for millennia to combat a whole range of ailments, at times to the chagrin of modern scientists who have struggled to explain their medical benefits.
However, a recent study by researchers at the University of Sydney has a popular ancient remedy, the elderberry fruit can help fight influenza
Conducted by Professor Fariba Deghani, Dr. Golnoosh Torabian and Dr. Peter Valtchev as part of the ARC Training Center for the Australian Food Processing Industry that was established within the university's Faculty of Engineering and IT, the study showed that compounds from elderberries can directly inhibit the virus's entry and replication in human cells, and can help strengthen the person's immune response to the virus.
Although elderberry's flu -fighting properties have long been observed, the group performed a comprehensive examination of the mechanism by which phytochemicals , compounds that positively effect health, from elderberries to combat influenza infections.
It inhibits the early stages of an infection by blocking key viral proteins responsible for both the viral attachment and entry into the host cells, "said Dr. Golnoosh Torabian.
The researchers used commercially farmed elderberries which were turned into a juice serum and were Applied to cells before and after they had been infected with the influenza virus
The phytochemicals from the elderberry juice were shown to be effective in stopping the virus infecting the cells, however to the surprise of the researchers they were even more effective at inhibiting viral propagation at later stages of the influenza cycle when the cells had already been infected with the virus
"This observation was quite surprising and rather significant because blocking the viral cycle at several stages has a higher chance of inhibiting the virus. viral infection, "explained Dr. Peter Valtchev.
" In addition, we identified that the elderberry solution also stimulated He cells to release certain cytokines, which are chemical messengers of the immune system for communication between different cell types to coordinate a more efficient response against the invading pathogen, "said Center Director, Professor Fariba Deghani.
The team also found that the elderberry's antiviral activity can be attributed to its anthocyanidin compounds ̵
Otherwise known as Sambucus nigra the elderberry is a small, antioxidant rich fruit common to Europe and North America, which is commonly used as a jam or wine. [Theinfluenzavirusisoneoftheleadingcausesofmortalityworldwideaffectingalmost10percentoftheworldpopulationandcontributingtoonemilliondeathsannuallyStorySource:
Materials provided by University of Sydney . Note: Content may be edited for style and length.