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Covid-19 nasal spray protects against infection for up to 48 hours



Anti-COVID-19 nasal spray, which protects against coronavirus infection for up to 48 hours, is ‘ready for use in humans’ and can be mass-produced in WEEK, researchers claim

  • Spray uses compounds already approved by regulators for human use
  • University of Birmingham researchers made the spray and said it is ‘ready to go’
  • Spray was shown to inhibit the activity of coronavirus in laboratory-based experiments
  • Would be used as well as max and social distancing in high risk scenarios

A nasal spray that claims to provide protection against Covid-19 infection for up to 48 hours may soon be available in the UK.

Chemicals already approved for human use have been combined to make the spray, and laboratory studies show that it inhibits the coronavirus’ ability to bind to human cells.

The spray is made from two main ingredients, called carrageenan and gellan, both of which are used in food science as thickeners.

Because the ingredients are already approved for human use, the developers say the product is ready for use as soon as it gets the go-ahead from the authorities.

Chemicals already approved for human use have been combined to make the spray, and laboratory studies show that it inhibits the coronavirus' ability to bind to human cells.

Chemicals already approved for human use have been combined to make the spray, and laboratory studies show that it inhibits the ability of the coronavirus to bind to human cells.

Lead author on paper, Dr. Richard Moakes, said: ‘This spray is made from readily available products already used in food and medicine, and we have deliberately built these conditions into our design process.

‘This means that with the right partners we could start mass production within a few weeks.’

The gellan component allows the spray to be administered as a fine mist and it covers the entire inside of the nose.

If the spray comes in contact with SARS-CoV-2, the virus that causes Covid-19, it catches it, envelops it and expels it either by swallowing or by blowing in the nose.

The researchers behind the project at the University of Birmingham say the spray can be particularly useful in high-risk situations, such as for healthcare professionals, flights or in classrooms.

The gellan component allows the spray to be administered as a fine mist, and once in the nose, it captures and encapsulates SARS-CoV-2, the coronavirus that causes Covid-19, and it is neutralized by swallowing or blowing into the nose ( lager)

The gellan component allows the spray to be administered as a fine mist, and once in the nose, it captures and encapsulates SARS-CoV-2, the coronavirus that causes Covid-19, and it is neutralized by swallowing or blowing into the nose ( lager)

Nasal drops made with chicken coravirus antibodies ‘confer short-term immunity to Covid-19’

Nasal drops made using coronavirus antibodies harvested from chicken eggs could provide short-term immunity to Covid-19, researchers have claimed.

Chickens produce antibodies against infections just as humans do, and the anti-infective chemicals are also found in high concentrations in their eggs.

Scientists use the birds to quickly produce antibodies to the coronavirus and extract them from their egg yolks in hopes that they can help humans.

They believe that if the chicken antibodies are integrated into a nasal spray or drops, they can provide short-term protection against Covid-19.

In situations where the risk of transmission is high, researchers envision using the spray in conjunction with pre-existing measures, such as social distances and face masks.

‘Products like these do not replace existing measures such as The use of a mask and washbasin, which will continue to be crucial in preventing the spread of the virus, ‘adds Dr. Moakes.

‘What this spray will do, however, is add another layer of protection to prevent and slow transmission.’

The results of the latest tests are available as a preview on the bioRxiv server.

Dr Simon Clarke, associate professor of cellular microbiology at the University of Reading, told MailOnline: ‘Some people use similar nasal sprays for colds, but they trust people to notice the symptoms in time, but Covid-19 only seems to cause symptoms when the virus have reached the lungs the spray reaches not so far down the airways in any significant amount.

‘It remains to be seen how it, if effective, could be used. It may be that it must be taken continuously to prevent infection. ‘

Stanford researchers had a similar mindset as the Birmingham academics and are also in the process of creating a preventative nasal spray.

But instead of using authorized compounds found in many foods, they use chicken antibodies harvested from their eggs.

Chickens produce antibodies against infections just as humans do, and the anti-infective chemicals are also found in high concentrations in their eggs.

But while the academics behind the project are bullish on its potential uses, others are more skeptical.

Simon Clarke, associate professor of cellular microbiology at the University of Reading, told The Times: ‘It could have some benefit, but it is believed that people are only infected through the nose.

‘This strategy would not stop the infection through the mouth or eyes.’

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