Meng, CFO of Chinese tech giant Huawei, was arrested by Canadian authorities on behalf of the United States in Vancouver on December 1.
The US government argues that Meng helped Huawei to evade US sanctions against Iran and has indicated that it will file a formal extradition request by January 30.
The Chinese government has repeatedly urged her to release and label the charges politically.
Speaking at the Beijing press conference, Canadian ambassador John McCallum seemed to suggest strained relations between the United States and Canada over the continuing fallout from the case.
"I think she has pretty good arguments on her side," McCallum said. "A political inclusion of Donald Trump's comments in her case. Two, an extraterritorial aspect to her case, and three, the issue of Iran's sanctions involved in her case, and Canada not signing on these Iran's sanctions. "
The Chinese foreign ministry spokeswoman Hua Chunying said Thursday that the case against Meng had" never been a normal trial. " 1
Since Meng's arrest, China has detained two Canadians suspected of "activities threatening China's national security." Another Canadian was sentenced to death after a Chinese court convicted him of drug trafficking, causing Canada to issue a travel warning to its citizens about the "risk of arbitrary enforcement of local laws" in China.
McCallum said the relations were strong between Ottawa and Beijing before the arrest and added he knew it had "anger China".
"I know this has anger China, but we have a extradition treaty system a law system that lies above the government, the government cannot change these things," he said.
US President Donald Trump complicated the situation in December by suggesting he could intervene in the legal saga if it would help his persecution of a trade deal with China.
"If I think it's good for what will be the biggest trade agreement ever made – which is very important – what's good for national security – I'd certainly intervene if I thought it was necessary, "Trump told Reuters.
] That helped burn the big stance in China that Mung's arrest was a political step from the Trump administration to leverage clashes between the two countries over trade and technology rather than law enforcement.
At that time, Canadian Foreign Minister Chrystia Freeland could reprimand Trump. "Our extradition partners should not try to politicize the extradition process or use it for anything but doing justice," she said.
On Wednesday, Canadian Prime Minister Justin Trudeau said he was determined to "ensure that the rule of law is properly and fully followed," adding that would include the possibility of Meng "mounting a strong defense."  As the pressure on the ambassador's comment, Trudeau said his government would ensure that the independence of Canada's justice system was "properly defended and properly supported."
McCallum's comments were met with dismay in parts of Canada, but Canadian Conservative opposition leader Andrew Scheer asked for the ambassador's dismissal.
"We cannot, on the one hand, go and defend our actions to the Chinese government by saying that these decisions are taken in arm's length … on the other hand, if the government uses our ambassador to China to interfere in the process of achieving a red result, "Scheer told CBC on Wednesday.
CNN's Steven Jiang, Paula Newton and Carly Walsh contributed to this article.