Anyone who usually takes a daily aspirin should know the risks involved, the researchers behind a new study say: while reducing the risk of heart attack or stroke, it risks serious internal bleeding.
In this study, we talk about adults without existing heart disease, and scientists say the potential dangers outweigh the potential benefits – so think twice about popping an aspirin a day in the future. 19659003] The new research is a meta-study of previous clinical trials looking at trends and patterns across more than 164,000 individuals, and it challenges conventional wisdom that daily aspirins are a safe way to reduce the risk of heart disease, especially for older people.
"This study shows that there is insufficient evidence to recommend routine aspirin use for the prevention of heart attack, stroke and cardiovascular death in humans without cardiovascular disease," says one of King & # 39; s scientists Sean Zheng. 39; s College London in the United Kingdom.
"There has been greater uncertainty about what to do in patients at higher risk of cardiovascular disease and in patients with diabetes. This study shows that while cardiovascular events can be reduced in these patients, these are matched Benefits of Increased Risk of Major Bleeding Events. "Even before this study arrived, the experts said that people should only take regular low doses of aspirin on a doctor's advice ̵
Now the picture is a little more clear. Over thousands of people taking part in the meta-study had those who took daily aspirin, a 0.38 percent lower absolute risk of heart attack, stroke or cardiovascular death.
At the same time, a daily aspirin habit was associated with a 0.47 percent higher absolute risk of severe internal bleeding. It emphasizes how important it is to start doing this before you have chatted to your doctor about it.
Kevin McConway from Open University in the UK who was not involved in the research explained how it would translate into real numbers for Rich Haridy at New Atlas.
With a daily aspirin, 57 are expected rather than 61 people per. 10,000 to suffer a heart attack or stroke; At the same time, 23 instead of 16 people per. 10,000 experience severe bleeding.
"This seriously asks if people who have not previously had heart attacks or strokes should take aspirin for the purpose of reducing future cardiovascular events," Zheng told Lisa Rapaport on Reuters.
The average average age of all participants was 62 (from 53 to 74). About half of them were followed for at least five years.
One of the limitations of the research is that the many studies looked at various different daily doses of aspirin – from 50 mg to 500 mg. Doctors usually do not prescribe anything higher than 100 mg a day.
Nevertheless, it is worth noting that patients and doctors weigh the benefits and disadvantages of using aspirin as a preventative measure and may consider alternative options (such as controlling blood pressure or stopping smoking) instead.
In an editorial accompanying study, Michael Gaziano of Brigham and Women & # 39; s Hospital in Boston, who was not involved in the main research, said that aspirin is still "an important drug" for the prevention of cardiovascular health issues as long as We use it wisely.
"Aspirin use requires discussion between the patient and their doctor with the knowledge that small potential cardiovascular benefits are weighed against the real risk of severe bleeding," Zheng says. 19659003] The research has been published in Journal of the American Medical Association .